Which of the Enzymes Unwinds the DNA Strands During Replication

Question

Which of the enzymes unwinds the DNA strands during replication?
A)helicase
B)topoisomerase
C)DNA ligase
D)single-stranded binding protein
E)primase

Accepted Answer

Helicase is responsible for unwinding the double-stranded DNA during replication by breaking the hydrogen bonds between the two strands, thus separating them. This allows for the other enzymes involved in replication to access each strand and carry out their respective functions.