What is the Role of DNA Ligase in the Elongation

Question

What is the role of DNA ligase in the elongation of the lagging strand during DNA replication?
A)It synthesizes RNA nucleotides to make a primer.
B)It catalyzes the lengthening of telomeres.
C)It joins Okazaki fragments together.
D)It unwinds the parental double helix.
E)It stabilizes the unwound parental DNA.

Accepted Answer

DNA ligase is responsible for joining the Okazaki fragments together on the lagging strand during DNA replication. Okazaki fragments are short fragments of DNA that are synthesized in the 5' to 3' direction on the lagging strand during replication. DNA ligase catalyzes the formation of a phosphodiester bond between the adjacent fragments to form a continuous DNA strand.