After Which Checkpoint is the Cell First Committed to Continue

Question

After which checkpoint is the cell first committed to continue the cell cycle through M?
A)G₀
B)G₁
C)G₂
D)S
E)previous M

Accepted Answer

The checkpoint at G1 is the point at which the cell is first committed to continue through the cell cycle to M phase. At this checkpoint, the cell checks for damage to DNA before deciding whether to move on to the S phase. If the DNA is damaged beyond repair, the cell may enter a quiescent state (G0) or undergo apoptosis. Once the DNA is deemed intact, the cell is committed to continue through the cell cycle to M phase.