An Inhibitor of Phosphodiesterase Activity Would Have Which of the Following

Question

An inhibitor of phosphodiesterase activity would have which of the following effects?
A)block the response of epinephrine
B)decrease the amount of cAMP in the cytoplasm
C)block the activation of G proteins in response to epinephrine binding to its receptor
D)prolong the effect of epinephrine by maintaining elevated cAMP levels in the cytoplasm
E)block the activation of protein kinase A

Accepted Answer

Inhibiting phosphodiesterase activity would decrease the breakdown of cAMP, leading to an accumulation of cAMP in the cytoplasm. This would prolong the effect of epinephrine, which activates cAMP-dependent pathways, by maintaining elevated cAMP levels in the cytoplasm.