During Cellular Respiration,acetyl CoA Accumulates in Which Location

Question

During cellular respiration,acetyl CoA accumulates in which location?
A)cytosol
B)mitochondrial outer membrane
C)mitochondrial inner membrane
D)mitochondrial intermembrane space
E)mitochondrial matrix

Accepted Answer

Acetyl CoA accumulates in the mitochondrial matrix during cellular respiration. This is because after pyruvate enters the mitochondria, it is converted to acetyl CoA in the mitochondrial matrix by the enzyme pyruvate dehydrogenase complex. The acetyl CoA is then used in the citric acid cycle to produce ATP through oxidative phosphorylation.