Question 106

(Multiple Choice)

Gaucher disease is the most common of lipid storage diseases in humans.It is caused
By a deficiency of an enzyme necessary for lipid metabolism.This leads to a collection of
Fatty material in organs of the body including the spleen,liver,kidneys,lungs,brain,and
Bone marrow.Using your knowledge of the structure of eukaryotic cells,identify the statement below that best explains how internal membranes and the organelles of cells would be involved
In Gaucher disease.


A)The mitochondria are most likely defective and do not produce adequate amounts of
ATP needed for cellular respiration.
B)The rough endoplasmic reticulum contains too many ribosomes which results in an
Overproduction of the enzyme involved in carbohydrate catalysis.
C)The lysosomes lack sufficient amounts of enzymes necessary for the metabolism of
Lipids.
D)The Golgi apparatus produces vesicles with faulty membranes that leak their contents
Into the cytoplasm of the cell.
E)The gap junctions are not functioning, and cells are not conveying to other cells that they have enough lipids.

Answer