Which of the Following Can Produce Linkage Disequilibrium

Question

Which of the following can produce linkage disequilibrium?
A) genetic drift
B) selection on genotypes of more than one locus
C) mixing two disparate populations, each of which is in linkage equilibrium
D) All of these choices can create linkage disequilibrium.

Accepted Answer

All three options can produce linkage disequilibrium. 
A) Genetic drift can cause a change in allele frequencies in a population, leading to LD between previously unlinked loci. 
B) Selection on genotypes of more than one locus can cause LD if certain combinations of alleles at different loci are favored. 
C) Mixing two disparate populations, each of which is in linkage equilibrium, can lead to LD between previously unlinked loci due to the differences in allele frequencies between populations.