Which of the Following is True About the Knockout Technique

Question

Which of the following is true about the knockout technique?
A) It compares the epistatic and additive effects of a disabled gene.
B) It uses a linkage map to examine the heritability of a gene that has been disabled.
C) It breaks gene-environment interactions by disabling a gene.
D) It compares the behavior of wild-type individuals and those with a disabled gene.
E) It allows estimation of heritability by disabling a gene.

Accepted Answer

The knockout technique involves disabling a gene to observe the difference in phenotype between organisms (or cells) with the gene disabled (knockout organisms) and those with the gene functioning normally (wild-type). This comparison helps in understanding the role and function of the specific gene.