Amethopterin is a Structural Analogue of _________

Question

Amethopterin is a structural analogue of _________.
A) Thiamine
B) GABA
C) Folate
D) MPPP
E) Mercapturic acid

Accepted Answer

Amethopterin, also known as methotrexate, is a structural analogue of folate (vitamin B9). It inhibits the enzyme dihydrofolate reductase, which is involved in the synthesis of tetrahydrofolate, a form of folate required for the synthesis of nucleotides.