The Lock and Key Model of Enzyme Activity Proposes That

Question

The lock and key model of enzyme activity proposes that each __________.
A) enzyme can react with only a single substrate
B) enzyme has a cofactor that promotes the catalytic activity
C) substrate has a specific cofactor that binds it to the enzyme
D) enzyme binds a specific substrate because the active site and substrate have complementary structures.
E) Both A and B are correct.

Accepted Answer

The lock and key model suggests that enzymes and substrates fit together with specificity, much like a lock and its key, due to the complementary shapes of the active site and the substrate. This model does not imply that enzymes can only react with a single substrate in all contexts (as some enzymes can act on multiple substrates), nor does it focus on cofactors in its basic premise.