Blocking Lactate Dehydrogenase in a Cell Producing ATP in the Absence

Question

Blocking lactate dehydrogenase in a cell producing ATP in the absence of oxygen would
A) not affect glycolysis.
B) halt the ETC that was functioning.
C) halt glycolysis.
D) allow two ATP molecules to be produced from each glycolysis cycle.

Accepted Answer

Blocking lactate dehydrogenase would prevent the conversion of pyruvate to lactate, which is necessary to regenerate NAD+ for glycolysis to continue in anaerobic conditions. Without NAD+, glycolysis would halt.