Which of the Following is Incorrect Regarding the Glucocorticoid Hormones

Question

Which of the following is incorrect regarding the glucocorticoid hormones?
A) They interact with receptors located in the plasma membrane of the cell.
B) After interacting with the receptor, they release HSP90.
C) The receptors form a homodimer that travels to the nucleus.
D) The homodimer interacts with GRE, activating transcription.

Accepted Answer

Glucocorticoid hormones interact with receptors located in the cytoplasm, not in the plasma membrane of the cell. The interaction leads to the release of HSP90, followed by the formation of a homodimer that travels to the nucleus, interacts with glucocorticoid response elements (GRE) in the DNA, and activate transcription.