What would be the result of a mutation in HSP90 that blocked HSP90's ability to bind to the glucocorticoid receptor?

A) Glucocorticoid receptor could not form a dimer.
B) The nuclear localization signal would no longer function.
C) Glucocorticoid regulated genes would not be controlled even in the absence of  glucocorticoid.
D) The hormone would not be able to bind to the glucocorticoid receptor.