Linus Pauling Demonstrated That

Question

Linus Pauling demonstrated that:
A) the structure of hemoglobin was altered by a mutation of a single gene.
B) mutations only caused defects in enzymes.
C) mutations alter the structure of RNA, but not proteins.
D) mutations were inherited.
E) the structure of hemoglobin was altered by mutations in any of a dozen genes.

Accepted Answer

Linus Pauling's work demonstrated that a mutation in a single gene could alter the structure of hemoglobin, leading to sickle cell anemia. This was a groundbreaking discovery in molecular biology, showing a direct link between genetic mutation and changes in protein structure.