Garrod First Proposed That

Question

Garrod first proposed that:
A) metabolic defects were due to the lack of an enzyme.
B) metabolic defects were due to excess enzyme production.
C) metabolic defects were due to chromosomal changes.
D) mutations were heritable.
E) metabolic defects did not occur in humans.

Accepted Answer

Garrod proposed the concept of "inborn errors of metabolism," suggesting that certain diseases were due to the lack of specific enzymes, not due to excess enzyme production, chromosomal changes, mutations, or the absence of metabolic defects in humans.