Under Which of the Following Situations Would Receptor Downregulation Most

Question

Under which of the following situations would receptor downregulation most likely occur?
A) The number of G proteins is too high.
B) The concentration of a hormone is too high.
C) The cell is unable to manufacture cyclic AMP.
D) The concentration of a neurotransmitter is too low.
E) The number of receptors in the plasma membrane is too low.

Accepted Answer

Receptor downregulation typically occurs in response to prolonged exposure to high concentrations of a ligand, such as a hormone. This is a cellular mechanism to prevent overstimulation and maintain homeostasis.