Although quite inefficient, cloning by nuclear transplantation can be successful, as exemplified by cloning of the famous Dolly. Such a success implies that …

A) nuclei can be reprogrammed by cytoplasmic factors in a foreign cytoplasm.
B) epigenetic changes in somatic cells are not functionally irreversible.
C) even a differentiated nucleus contains a complete genome, capable of supporting the development of an entire organism.
D) All of the above.