Mutation in Which of the Following Genes is Most Prevalent

Question

Mutation in which of the following genes is most prevalent in human colorectal cancer cells?
A) K-Ras
B) β-Catenin
C) Apc
D) p53
E) MLH

Accepted Answer

The Apc tumor suppressor gene is mutated (and is defective) in over 80% of colorectal cancers.