In the Active State of the Integrin Dimer, …

Question

In the active state of the integrin dimer, …
A) both intracellular and extracellular binding sites are exposed.
B) the intracellular binding sites are inaccessible, while the extracellular binding sites are exposed.
C) the intracellular binding sites are exposed, while the extracellular binding sites are inaccessible.
D) both intracellular and extracellular binding sites are inaccessible.

Accepted Answer

In the active state of integrins, the two subunits in each dimer are unhooked at the membrane to expose the binding sites at both sides of the membrane.