Indicate whether each of the following descriptions better applies to the intracellular (I) or extracellular (E) domain of integrins. Your answer would be a four-letter string composed of letters I and E only, e.g. EEEE.
( ) It binds to talin.
( ) It binds to the RGD tripeptide motif.
( ) It is bulkier.
( ) It contains divalent cation-binding domains.