Which of the Following is True Regarding Fibril-Associated Collagens Such

Question

Which of the following is true regarding fibril-associated collagens such as type IX collagen?
A) They aggregate with one another to form long fibrils in the extracellular space.
B) They lack the triple-stranded helical structure found in other collagens.
C) They are more flexible than collagens of types I to IV.
D) They are the most common among collagens.
E) All of the above.

Accepted Answer

Fibril-associated collagens bind in a periodic manner to fibrils made of fibrillar collagens (e.g. type I). The presence of nonhelical interruptions within their triple-stranded helical structure makes these fibril-associated collagens more flexible than fibrillar collagen molecules.