Mitotic segregation of organelles can lead to so-called homoplasmy, when all organelles in each cell carry the same genome. In contrast, heteroplasmy describes the presence of organelles within the same cell that are different with respect to their genomic sequences. Would you expect a defect in the mitochondrial fusion machinery to favor homoplasmy (M) or heteroplasmy (T)? Write down M or T as your answer.
Answers