How many protons [or, more accurately, hydronium ions (H₃O⁺)] are there in a spherical lysosome that is about 0.6 µm in diameter and maintains an interior pH of about 5.0? Recall that the volume of a sphere of radius r is calculated as V = 4/3 × π × r³, and that pH = -log [H⁺]. Avogadro's constant is approximately 6 × 10²³ molecules/mole.