The Cytoplasmic C-Terminal KKXX Sequence of Transmembrane Proteins Interacts with …

Question

The cytoplasmic C-terminal KKXX sequence of transmembrane proteins interacts with …
A) t-SNAREs
B) v-SNAREs
C) AP2
D) COPI coatomers
E) COPII coatomers

Accepted Answer

By binding to the COPI coats, the retrieval signal mediates the retrograde transport of the protein back to the ER.