Phosphoinositides mark different cellular membranes and play key roles in protein trafficking inside the cell. Among them, PI(4,5)P₂ is involved in receptor-mediated endocytosis as well as phagocytosis at the plasma membrane. This phosphoinositide …
A) is bound by the adaptor protein AP2. B) is bound by the GTPase dynamin. C) is depleted from clathrin-coated vesicles to promote their uncoating. D) All of the above.