Question 59

(Short Answer)

Indicate true (T) and false (F) statements below regarding mRNA stability and degradation. Your answer would be a four-letter string composed of letters T and F only, e.g. TTFT.
( ) Any factor that affects the translation efficiency of an mRNA tends to have the opposite effect on its degradation.
( ) Decapping of mRNA normally occurs after poly-A tail shortening removes the poly-A tail and starts chewing into the 3?-UTR.
( ) Most mRNA decay in the cells generally proceeds via endonucleolytic cleavage.
( ) As a general rule, eukaryotic mRNAs have a shorter half-life compared to bacterial mRNAs.

Answer


Eukaryotic mRNAs are generally more st...

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