The Modified Nucleotide Shown Below is Normally Found in Mature

Question

The modified nucleotide shown below is normally found in mature... 
A) tRNAs. 
B) ribosomes. 
C) spliceosomes. 
D) snoRNAs. 
E) All of the above.

Accepted Answer

The modified nucleotide is pseudouridine, one of the most abundant modified nucleotides in cellular RNA, and it is found in tRNAs, rRNAs, snRNAs, and snoRNAs. The "guide" snoRNAs in the nucleolus are themselves involved in the pseudouridylation of the other RNAs.