Question 49

(Short Answer)

The RecA/Rad51 protein carries out strand exchange during homologous recombination. Indicate true (T) and false (F) statements about this process below. Your answer would be a four-letter string composed of letters T and F only, e.g. FFFF.
( ) RecA hydrolyzes ATP upon binding to the invading DNA strand.
( ) RecA forces the invading strand into a conformation that fully mimics the geometry of a long DNA double helix.
( ) Sampling of the homologous duplex by the invading strand is likely to occur in triplet nucleotide blocks.
( ) RecA-bound, invading, single-stranded DNA binds and destabilizes the homologous duplex to allow the sampling of its sequence by base-pairing.

Answer


RecA binds cooperatively to the invadi...

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