Indicate true (T) and false (F) descriptions below regarding the nucleotide excision repair pathway. Your answer would be a four-letter string composed of letters T and F only, e.g. FFFF.
( ) It involves recognition of distortions in the DNA double helix rather than specific base changes.
( ) It involves endonucleolytic cleavage and helicase-mediated strand removal.
( ) It involves cleavage by the AP endonuclease.
( ) It is coupled to the DNA transcription machinery of the cell.