Which of the following features is common between the replication origins in Escherichia coli and Saccharomyces cerevisiae?

A) They both normally exist in one copy per genome.
B) Both are specified by DNA sequences of tens of thousands of nucleotide pairs.
C) Both contain sequences that attract initiator proteins, as well as stretches of DNA rich in A-T base pairs.
D) Both contain GATC repeats that are methylated to prevent the inappropriate "firing" of the origin.
E) All of the above.