Switch proteins that bind and hydrolyze GTP are ubiquitous cell regulators in a wide variety of molecular processes. Which of the following statements is NOT true regarding these proteins?
A) EF-Tu is an example of such proteins.
B) GTP hydrolysis by the GTPase generally renders it inactive.
C) Activation of the GTPase involves addition of a phosphate group to its bound guanine nucleotide.
D) Guanine nucleotide exchange factors generally activate the GTPases.
E) Guanine nucleotide exchange factors accelerate the release of bound GDP from the GTPases.