Question 27

(Multiple Choice)

The phosphofructokinase (PFK) enzyme is one of the key players in the glycolytic pathway in which glucose eventually breaks down into pyruvate, some ATP is generated, and some NAD⁺ is reduced. PFK catalyzes the committed step in the pathway and is under extensive regulation. Which of the following compounds would you expect to activate PFK?


A) ADP
B) NADH
C) Pyruvate
D) ATP
E) All of the above

Answer