The observation that proteins often renature into their original conformations after they have been unfolded by denaturing solvents implies that …

A) the information needed to specify the three-dimensional shape of a protein is encoded in its amino acid sequence.
B) the cell does not need molecular chaperones for survival.
C) the final folded structure of a protein is usually NOT the one with the lowest free energy.
D) each protein folds into several different conformations inside the cell.
E) All of the above.