Which of the Following is Both a Hypersensitivity Disorder and an Autoimmune

Question

Which of the following is both a hypersensitivity disorder and an autoimmune disorder?
A) anaphylaxis
B) glomerulonephritis
C) graft rejection
D) hemolytic disease of the newborn
E) rheumatoid arthritis

Accepted Answer

Rheumatoid arthritis is both a hypersensitivity disorder (Type III) and an autoimmune disorder. It is characterized by chronic inflammation in the joints leading to destruction of cartilage and bone. The immune response is directed against self-antigens, particularly IgG, causing immune complex formation and subsequent tissue damage.