Viral Neutralization Testing is Based on the Fact That

Question

Viral neutralization testing is based on the fact that
A) antibodies can be produced against the toxin of a pathogen.
B) antibodies have different molecular weights.
C) viruses introduced into appropriate cell cultures have a cytopathic effect.
D) the gene for a pathogen's antigen can be isolated and introduced into a host cell by way of a plasmid.
E) antibodies to certain microbes can be given a fluorescent label.

Accepted Answer

The cytopathic effect refers to the damage caused to the host cell by the introduced virus. If serum containing antibodies against the specific virus is added to the cell culture, it will neutralize the virus and prevent the cytopathic effect. This forms the basis of viral neutralization testing.