Monoclonal Antibodies are Obtained From

Question

Monoclonal antibodies are obtained from
A) human serum.
B) animal serum.
C) hybridomas.
D) human B cells in culture.
E) both human and animal serum

Accepted Answer

Monoclonal antibodies are produced by hybridomas, which are created by fusing an immortal cancerous cell line with a B cell that produces a specific antibody of interest. Therefore, choice C (hybridomas) is the correct answer. Choices A and B (human and animal serum) are incorrect because monoclonal antibodies are not obtained from serum alone. Choice D (human B cells in culture) is not entirely incorrect, as B cells are used to create hybridomas, but it is not the definitive source of monoclonal antibodies. Choice E (both human and animal serum) is also incorrect for the same reason as choices A and B.