Immature B Lymphocytes Undergo Clonal Deletion in the Bone Marrow

Question

Immature B lymphocytes undergo clonal deletion in the bone marrow.

Accepted Answer

Immature B lymphocytes undergo clonal deletion in the bone marrow as a part of the process of negative selection to avoid the production of self-reactive antibodies. Those that recognize self-antigens are eliminated by apoptosis, while those that pass this test will mature and leave the bone marrow.