The Antibody-Binding Site of an Antibody is Made Up Of

Question

The antibody-binding site of an antibody is made up of
A) portions of both of the heavy chains only.
B) the variable regions of the heavy chains.
C) the light chains only.
D) the variable regions of both light and heavy chains.
E) one heavy chain.

Accepted Answer

The antibody-binding site, also known as the antigen-binding site, is made up of the variable regions of both light and heavy chains. These regions contain the hypervariable loops or complementarity-determining regions (CDRs) that directly interact with the antigen.