Which of the Following Substances Contributes to the Edema Associated

Question

Which of the following substances contributes to the edema associated with inflammation?
A) leukotrienes
B) histamine
C) interferon
D) defensin
E) both leukotrienes and histamine

Accepted Answer

Leukotrienes and histamine are both inflammatory mediators that contribute to the development of edema in response to inflammation. Leukotrienes increase vascular permeability and histamine causes vasodilation and contraction of endothelial cells, leading to increased leakage of fluid into tissues.