The Antifungals Known as Polyenes Interact with ________, a Lipid

Question

The antifungals known as polyenes interact with ________, a lipid unique to fungus membranes.
A) cholesterol
B) ergosterol
C) mycolic acid
D) phospholipid
E) glycolic acid

Accepted Answer

Polyenes such as amphotericin B interact with ergosterol, a lipid unique to fungus membranes. Ergosterol is the target of polyenes, leading to disruption of the membrane and subsequent cell death.