A Drug is Structurally Similar to PABA and Inhibits Folic

Question

A drug is structurally similar to PABA and inhibits folic acid synthesis. It is most likely a(n)
A) nucleic acid analog.
B) penicillin.
C) tetracycline.
D) azole.
E) sulfonamide.

Accepted Answer

The drug is structurally similar to PABA and inhibits folic acid synthesis, which are characteristics of sulfonamides. Sulfonamides competitively inhibit the enzyme dihydropteroate synthase, which is needed for the production of folic acid.