Which of the following is TRUE concerning the structure and function of enzymes?
A) All enzymes bind cofactors necessary for their function. B) An apoenzyme is a combination of a cofactor bound to a holoenzyme. C) Enzymes can function at a wide range of pH. D) Competitive inhibition of an enzyme occurs when an inhibitor binds to an allosteric site on the enzyme. E) After an enzyme has catalyzed a reaction, it resumes its original shape and can interact with a new substrate molecule.