Which of the Following Statements Concerning Glycolysis is TRUE

Question

Which of the following statements concerning glycolysis is TRUE?
A) The first step of glycolysis involves oxidative phosphorylation.
B) The glycolytic pathway is cyclical.
C) Glucose is activated by substrate-level phosphorylation.
D) Ribulose 5-phosphate is an intermediate of glycolysis.
E) Two NADH molecules are reduced during glycolysis.

Accepted Answer

Glucose activation in glycolysis involves substrate-level phosphorylation, where phosphate groups are transferred from high-energy compounds (like ATP) to glucose, making it more reactive. This is essential for the initial steps of glycolysis, where glucose is phosphorylated to glucose-6-phosphate.