Which of the Following Statements Best Describes a Key Aspect

Question

Which of the following statements best describes a key aspect of a G protein signaling pathway?
A) A G protein-coupled receptor is active when bound to GTP.
B) A G protein bound is active when bound to GTP.
C) A G protein bound is active when bound to GDP.
D) A G protein is activated by hydrolysis of bound GTP.

Accepted Answer

G proteins are molecular switches that are active when bound to GTP and inactive when bound to GDP. This is a fundamental aspect of how G protein signaling pathways operate, with the exchange of GDP for GTP triggering the active state of the G protein.