The Alpha-Amanitin Toxin Exerts Its Toxic Effects by Blocking Which

Question

The alpha-amanitin toxin exerts its toxic effects by blocking which of the following?
A) DNA polymerase
B) RNA polymerase
C) ligase
D) topoisomerase

Accepted Answer

Alpha-amanitin, a toxin found in certain species of mushrooms, exerts its toxic effects by inhibiting RNA polymerase, particularly RNA polymerase II in eukaryotes, which is crucial for mRNA synthesis.