Which of the Following is the Function of a Coactivator

Question

Which of the following is the function of a coactivator?
A) It unwinds the promoter DNA, allowing transcription to begin.
B) It recognizes and binds to the TATA box of a protein-coding gene's promoter.
C) It binds to the promoter proximal elements to stimulate transcription initiation.
D) It forms a bridge between the activators at the enhancer and the proteins at the promoter.

Accepted Answer

Coactivators function as intermediary molecules that form a bridge between transcriptional activators, which are bound to enhancers, and the basal transcription machinery located at the promoter. This interaction is crucial for enhancing the efficiency of transcription initiation.