Which of the Following Occurs in the Formation of Mineralized

Question

Which of the following occurs in the formation of mineralized bone matrix? A) Blood calcium is elevated. B) Hydrogen ions form an acid environment in bone matrix. C) Ca²⁺ is actively transported from bone matrix to the blood. D) The protein components of bone matrix are digested. E) Osteoblasts form collagen and proteoglycans.

Accepted Answer

Osteoblasts are responsible for forming the collagen and proteoglycan components of bone matrix. Option A is incorrect because elevated blood calcium levels occur as a result of bone resorption, not bone formation. Option B is incorrect because an alkaline environment is needed for the formation of mineralized bone matrix. Option C is incorrect because Ca²⁺ is not a known compound involved in bone formation. Option D is incorrect because the protein components of bone matrix are not digested during bone formation, but rather laid down by osteoblasts.