Receptors for Most Water-Soluble Hormones are Located

Question

Receptors for most water-soluble hormones are located
A) in the cytoplasm of their target cells.
B) on the plasma membrane of their target cells.
C) in the lysosomes of their target cells.
D) on the nuclear membrane of their target cells.
E) on the endoplasmic reticulum of their target cells.

Accepted Answer

Water-soluble hormones cannot cross the hydrophobic plasma membrane, so their receptors are located on the plasma membrane of their target cells. This activates a signal transduction cascade within the cell that ultimately changes cell behavior. The other options (A, C, D, E) are incorrect because they do not represent the location of receptors for water-soluble hormones.