Which of the Following is a Function of the Substantia

Question

Which of the following is a function of the substantia nigra?
A) It integrates information from the cerebrum and cerebellum and issues involuntary motor commands concerned with the maintenance of muscle tone and limb position.
B) It integrates visual information with other sensory input.
C) It regulates the motor output of the basal nuclei.
D) It initiates reflex responses to auditory stimuli.
E) It functions in the automatic processing of incoming sensations and outgoing motor commands.

Accepted Answer

The substantia nigra is a structure in the midbrain that is responsible for regulating the motor output of the basal nuclei. It is particularly important in the control of voluntary movements, including the initiation of movements and the maintenance of muscle tone. Dysfunction of the substantia nigra is associated with Parkinson's disease, a neurological disorder characterized by tremors, rigidity, and difficulty initiating movements.