Why Does a Skeletal Muscle Fiber Have More Than One

Question

Why does a skeletal muscle fiber have more than one nucleus?
A) During development, groups of embryonic cells called myoblasts fuse together to form a single muscle fiber.
B) During development, the nucleus of each myoblast replicates several times.
C) During development, the sarcolemmae of newly formed muscle fibers disintegrate, making many muscle cells into one.
D) During muscular activity, parts of each muscle fiber break down, and the remaining parts, including their nuclei, fuse into new combination fibers.
E) All of the answers are correct.

Accepted Answer

During development, groups of embryonic cells called myoblasts fuse together to form a single muscle fiber. Each myoblast has its own nucleus, and when they fuse together, their nuclei also combine. Therefore, a single muscle fiber can have multiple nuclei.